Rohit Dnyansagar
Skilled bioinformatician with a background in evolutionary, genetic and epigenetic studies
Strong grip over bioinformatics algorithms and a good understanding of biology and medicine
Proficient in an array of bioinformatics software and tools with strong programming and statistical skills
Very good oral and written communication in English
Team player, able to work in and coordinate collaborative studies
Skills
Skills listed here are bioinformatics skills although I also have pharmaceutical science education
Operating systems
- Unix
- Windows
- macOS
Programming languages
- Python
- R
- R Bioconductor
- Bash
- Perl
Bioinformatics Applications
- Molecular evolutionary analysis
- MiRNA analysis
Next Generation Sequencing (NGS)
- RNA-seq
- ChIP-seq
- ATAC-seq
- scRNA-seq
- SNP/Variant analysis
Statistics
- Hypothesis testing
- Regression models
Machine learning
- Regression models
- Support vector machines
- K-mer counting
- Clustering
Research
PhD under Prof. Ulrich Technau
University of Vienna, Austria, Dec 2014 – Dec 2019
- Comparative transcriptomic analysis of cryptic Edwardsiidae species to resolve species complex and to study phylogeography and speciation.
- The evolution of gene regulatory networks in animal development: Role of brachyury in “mesoderm” determination in metazoans
- Conservation and turnover of microRNAs and their mRNA targets in Cnidaria
Visiting researcher with Prof. N. Manoj
Indian Institute of Technology Madras, Chennai, Feb 2014 – Aug 2014
- Data mining for meta-analysis of DNA methylation across healthy human tissues with focus on brain.
Master thesis and project work under Prof. Helgi Schiöth
Uppsala University, Sweden, Aug 2012 – Dec 2013
- Study of GPCR receptors in marine demosponge Amphimedon queenslandica and its evolutionary analysis
- Differential expression analysis (RNA-seq) to study effects of ETV5 homologue Ets96B on obesity
- Phylogenetic and protein domain analysis of Coronin 7 family of proteins
- Metazoan repertoire of Potassium (K+) Channel Tetramerization Domain (KCTD) containing proteins
Publications
- Schwaiger, M*.,Andrikou, C.*, Dnyansagar, R.*, Zimmerman, B., Ferrer Murguia, P., Genikhovich, G., & Technau, U. (In preparation). The evolution of gene regulatory networks in animal development: Genome-wide identification of target genes of “mesoderm” determinants in metazoans.
- Praher, D., Zimmermann, B., Dnyansagar, R., Miller, D. J., Friis-Møller, L., Modepalli, V., … Technau, U. (Manuscript submitted). Conservation and turnover of microRNAs and their mRNA targets in Cnidaria.
- Dnyansagar, R.*, Zimmermann, B*., Moran, Y., Praher, D., Sundberg, P., Møller, L. F., & Technau, U. (2018). Dispersal and speciation: The cross Atlantic relationship of two parasitic cnidarians Molecular Phylogenetics and Evolution, 126, 346–355. doi:10.1016/j.ympev.2018.04.035
- Williams, M. J., Klockars, A., Eriksson, A., Voisin, S., Dnyansagar, R., Wiemerslage, L., … Schiöth, H. B. (2016). The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder. PLOS Genetics, 12(6), e1006104. doi:10.1371/journal.pgen.1006104
- Eriksson, A., Williams, M. J., Voisin, S., Hansson, I., Krishnan, A., Philippot, G., Dnyansagar, R… Schiöth, H. B. (2015).Implication of coronin 7 in body weight regulation in humans, mice and flies. BMC Neuroscience, 16, 13. doi:10.1186/s12868-015-0151-9
- Krishnan, A*., Dnyansagar, R*., Almén, M. S., Williams, M. J., Fredriksson, R., Manoj, N., & Schiöth, H. B. (2014). The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals. BMC Evolutionary Biology, 14, 270. doi:10.1186/s12862-014-0270-4